Cannabis. Marijuana. Cannabinoids. CBD. THC. Cannabis has been around almost forever, with quite the circular debate on its safety, efficacy, and, of course, legality across the globe. Before getting lost in the weeds, we need to discuss the basic pharmacology of all things cannabis, starting with some basic botanical “farm” information and a review of the human endocannabinoid system (ECS) before then venturing into the complexities of its pharmacology.