Drug shortages continue to challenge healthcare systems across the United States, affecting medication availability, patient safety, pharmacy workflow, and healthcare costs. Pharmacy technicians play a critical role in recognizing shortages, managing inventory, communicating with the pharmacy team, and supporting continuity of patient care. This continuing education activity will review the current landscape of drug shortages, common causes, and their impact on pharmacy practice. Participants will learn how to utilize national drug shortage resources, implement practical inventory management strategies, and collaborate effectively with pharmacists and healthcare providers to minimize the effects of medications shortages. Real-world case examples will provide opportunities to apply these concepts to everyday pharmacy practice.