Uses for peptide-based therapies in humans continue to expand beyond endocrine disorders, oncology treatments, and weight loss. As the uses for these medications grow, pharmacists and pharmacy technicians must be knowledgeable on the pharmacology, handling, and unique regulatory considerations for peptide-based therapies. These therapies are often distributed via provider’s offices or wellness-based clinics. Therefore, pharmacy professionals are likely to be consulted for practical knowledge to ensure the safe and effective use of peptides in patients.